It turns out that NMN can improve eye aging in many ways, which has been proved by a number of studies
A number of studies have found that NMN shows multiple potential in improving eye aging.
NMN improves retinal mitochondrial function
Research background:
A research team at the University of Minnesota has found that NMN helps improve retinal mitochondrial function to treat age-related macular degeneration (AMD).
AMD is the leading cause of blindness in the elderly, and the key factor behind it is mitochondrial dysfunction, which is unable to provide adequate energy for retinal pigment epithelial cells (RPE), resulting in RPE cell death.
Mechanism of action:
NMN can significantly improve mitochondrial function and increase the production of ATP (adenosine triphosphate) energy molecules, which in turn has a positive impact on eye function.
This improvement takes effect very quickly and can reach its peak effect within 24 hours after use.
Protects the optic nerve and photoreceptors
Research evidence:
A research team from Harvard Medical School published research results in the journal Aging, indicating that NMN can significantly increase the level of NAD+, SIRT1 protein expression and heme oxygenase-1 expression, which has a neuroprotective effect on photoreceptors after oxidative damage, and can inhibit the further deterioration of retinal detachment and other diseases.
Specific role:
By boosting NAD+ levels, NMN activates the long-lived protein SIRT1, which plays an important role in retinal development and survival.
In addition, NMN inhibits retinal inflammation, alleviates oxidative stress, and has a protective effect in the late stages of retinal detachment.
Increased tear production
The study found:
The research team at Washington University in St. Louis found that among the multiple effects of Nicotinamide Mononucleotide in improving metabolism and regulating immunity, it also includes improvements in eye function.
They assessed tear production in both control and NMN group mice and found that Nicotinamide Mononucleotide increased tear production.
Significance: As people age, the function of the lacrimal glands declines, leading to eye problems such as dry eye.
NMN helps alleviate these problems by increasing tear production, keeping the eye surface moist and healthy.
Regulates calcium ion signaling in optic nerve cells
Mechanism of action:
NMN can regulate calcium ion signal transmission in optic nerve cells,
regulate intracellular and intracellular ion balance by affecting the expression and function of SWELL1 and TRPM3 plasma channels,
and prevent cell death and retinal damage caused by disordered release of calcium ions.
Comprehensively improve eye health
Overall effect: Combining the effects of the above aspects,
NMN can significantly improve eye health and delay eye problems caused by aging.
It not only has a potential therapeutic effect on age-related eye diseases such as AMD and retinal detachment,
but also can improve common eye disorders such as dry eye.
